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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">sechenov</journal-id><journal-title-group><journal-title xml:lang="en">Sechenov Medical Journal</journal-title><trans-title-group xml:lang="ru"><trans-title>Сеченовский вестник</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2218-7332</issn><issn pub-type="epub">2658-3348</issn><publisher><publisher-name>Сеченовский Университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47093/2218-7332.2026.17.1.30-40</article-id><article-id custom-type="elpub" pub-id-type="custom">sechenov-1416</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>INTERNAL MEDICINE</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ВНУТРЕННИЕ БОЛЕЗНИ</subject></subj-group></article-categories><title-group><article-title>The influence of ChatGPT on medical student learning: a systematic review of educational outcomes and cognitive impact</article-title><trans-title-group xml:lang="ru"><trans-title>Влияние ChatGPT на обучение студентов медицинских вузов: систематический обзор образовательных результатов и когнитивного воздействия</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-1086-6790</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тан</surname><given-names>Ф.И.Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Tan</surname><given-names>F.Y.S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тан Феликс И Шуэн - врач, медицинский факультет.</p><p>Ул. Джалан Бату Хампар, д. 2, район Букит Бару, Малакка, 75150</p></bio><bio xml:lang="en"><p>Felix Y.S. Tan - physician, Faculty of Medicine.</p><p>2, Jalan Batu Hampar, Bukit Baru, Melaka, 75150, Malaysia</p></bio><email xlink:type="simple">ftan1106@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-9369-8656</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Анг</surname><given-names>Л.Ч.</given-names></name><name name-style="western" xml:lang="en"><surname>Ang</surname><given-names>L.C.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анг    Лидия         Ченг - врач, медицинский        факультет.</p><p>Ул. Джалан Бату Хампар, д. 2, район Букит Бару, Малакка, 75150</p></bio><bio xml:lang="en"><p>Lydia C. Ang - physician, Faculty of Medicine.</p><p>2, Jalan Batu Hampar, Bukit Baru, Melaka, 75150, Malaysia</p></bio><email xlink:type="simple">lydiaang0308@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-6937-1608</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ибрахим</surname><given-names>Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Ibrahim</surname><given-names>R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ибрахим     Рахима - врач,      медицинский        факультет.</p><p>Ул. Джалан Бату Хампар, д. 2, район Букит Бару, Малакка, 75150</p></bio><bio xml:lang="en"><p>Rahima Ibrahim - physician, Faculty of Medicine.</p><p>2, Jalan Batu Hampar, Bukit Baru, Melaka, 75150</p></bio><email xlink:type="simple">rahimamsufms@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-2363-7358</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абдул Маджид</surname><given-names>М.</given-names></name><name name-style="western" xml:lang="en"><surname>Abdul Majeed</surname><given-names>M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Абдул Маджид Мунавварах - врач, медицинский факультет.</p><p>Ул. Джалан Бату Хампар, д. 2, район Букит Бару, Малакка, 75150</p></bio><bio xml:lang="en"><p>Munawwarah Abdul Majeed - physician, Faculty of Medicine.</p><p>2, Jalan Batu Hampar, Bukit Baru, Melaka, 75150</p></bio><email xlink:type="simple">munawwarahmajeed@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-7178-1668</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мохд Арис</surname><given-names>М.А.Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Mohd Aris</surname><given-names>M.A.H.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мохд Арис Мохд Алифф Хайкал - врач, медицинский факультет.</p><p>Ул. Джалан Бату Хампар, д. 2, район Букит Бару, Малакка, 75150</p></bio><bio xml:lang="en"><p>Mohd Aliff H. Mohd Aris - physician, Faculty of Medicine.</p><p>2, Jalan Batu Hampar, Bukit Baru, Melaka, 75150</p></bio><email xlink:type="simple">aliffhaiqal731@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8836-5746</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Джордж</surname><given-names>Ш.Д.</given-names></name><name name-style="western" xml:lang="en"><surname>George</surname><given-names>S.D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Джордж Шерли Дебора - канд. мед. наук, кафедра физиологии медицинского факультета.</p><p>Ул. Джалан Бату Хампар, д. 2, район Букит Бару, Малакка, 75150</p></bio><bio xml:lang="en"><p>Sherly D. George - Cand. of Sci. (Medicine), Department of Physiology, Faculty of Medicine.</p><p>2, Jalan Batu Hampar, Bukit Baru, Melaka, 75150</p></bio><email xlink:type="simple">sherly.george@manipal.edu.my</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Малайзийский университетский колледж Манипал</institution><country>Малайзия</country></aff><aff xml:lang="en"><institution>Manipal University College Malaysia (MUCM)</institution><country>Malaysia</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>12</day><month>06</month><year>2026</year></pub-date><volume>17</volume><issue>1</issue><fpage>30</fpage><lpage>40</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Tan F., Ang L., Ibrahim R., Abdul Majeed M., Mohd Aris M., George S., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Тан Ф., Анг Л., Ибрахим Р., Абдул Маджид М., Мохд Арис М., Джордж Ш.</copyright-holder><copyright-holder xml:lang="en">Tan F., Ang L., Ibrahim R., Abdul Majeed M., Mohd Aris M., George S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.sechenovmedj.com/jour/article/view/1416">https://www.sechenovmedj.com/jour/article/view/1416</self-uri><abstract><sec><title>Aim</title><p>Aim. To evaluate whether the use of ChatGPT as a supplement to usual teaching improves medical students’ shortterm knowledge, clinical reasoning, and near-term performance.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. We systematically searched PubMed, Scopus, ScienceDirect, SpringerLink, and Web of Science on 25 June 2025, for studies involving medical students that evaluated ChatGPT as a supplement to teaching and reported objective educational outcomes. Two independent reviewers screened records, extracted data, and assessed the risk of bias. A narrative synthesis was then conducted due to the level of heterogeneity in interventions and outcome measures across the studies.</p></sec><sec><title>Results</title><p>Results. Three randomized trials conducted in Germany, Turkey, and China met the inclusion criteria. ChatGPTsupported interventions improved or at least maintained short-term educational outcomes over the control groups for knowledge tests, clinical reasoning, and some of the Mini-Clinical Evaluation Exercise (Mini-CEX) domains.</p><p>Structured and immediate ChatGPT feedback improved Clinical Reasoning Indicator-History Taking Inventory scores after a simulated patient encounter, and ChatGPT-generated explanations were not inferior to expert feedback in overall key-features question performance but were less effective for more complex items, where expert feedback remained superior. Overall, the risk of bias was judged to be low to some concerns, with likely unblinded Mini-CEX assessment noted as a significant limitation.</p></sec><sec><title>Conclusion</title><p>Conclusion. ChatGPT used as a supervised adjunct to teaching showed value for short-term knowledge acquisition and clinical reasoning development.</p></sec></abstract><trans-abstract xml:lang="ru"><sec><title>Цель</title><p>Цель. Оценить, способствует ли использование ChatGPT в качестве дополнения к традиционному обучению улучшению краткосрочного уровня знаний студентов-медиков, клинического мышления и ближайших учебных результатов.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. 25 июня 2025 г. был проведен систематический поиск исследований в базах данных PubMed, Scopus, ScienceDirect, SpringerLink и Web of Science. В обзор включались работы с участием студентов-медиков, в которых ChatGPT использовался как дополнение к обучению и оценивались объективные образовательные результаты. Два независимых рецензента осуществляли отбор публикаций, извлечение данных и оценку риска систематической ошибки. В связи с неоднородностью вмешательств и показателей исходов был выполнен нарративный синтез данных.</p></sec><sec><title>Результаты</title><p>Результаты. Критериям включения соответствовали три рандомизированных исследования, проведенных в Германии, Турции и Китае. Использование ChatGPT в образовательных вмешательствах способствовало улучшению либо по меньшей мере сохранению краткосрочных учебных результатов по сравнению с контрольными группами в отношении тестов знаний, клинического мышления и ряда доменов Mini-Clinical Evaluation Exercise (Mini-CEX). Структурированная и немедленная обратная связь с использованием ChatGPT улучшала показатели Clinical Reasoning Indicator–History Taking Inventory после взаимодействия с симулированным пациентом. Объяснения ответов, сгенерированные ChatGPT, не уступали экспертной обратной связи по общему результату выполнения заданий формата key-features, однако были менее эффективны при решении более сложных вопросов, где экспертная обратная связь имела преимущество. Общий риск систематической ошибки был оценен как низкий или вызывающий некоторые опасения; существенным ограничением являлась вероятная неослепленная оценка Mini-CEX.</p></sec><sec><title>Заключение</title><p>Заключение. Использование ChatGPT в качестве контролируемого дополнительного инструмента обучения продемонстрировало эффективность в отношении краткосрочного усвоения знаний и формирования клинического мышления.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>искусственный интеллект</kwd><kwd>додипломная подготовка врачей</kwd><kwd>медицинское образование</kwd><kwd>клиническое мышление</kwd><kwd>проблемно-ориентированное обучение</kwd><kwd>образовательные инновации</kwd></kwd-group><kwd-group xml:lang="en"><kwd>artificial intelligence</kwd><kwd>undergraduate medical training</kwd><kwd>medical education</kwd><kwd>clinical reasoning</kwd><kwd>problembased learning</kwd><kwd>educational innovation</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование выполнено без спонсорской поддержки (за счет собственных средств)</funding-statement><funding-statement xml:lang="en">The study was unfunded (own resources).</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Abouammoh N., Alhasan K., Aljamaan F., et al. 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