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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">sechenov</journal-id><journal-title-group><journal-title xml:lang="en">Sechenov Medical Journal</journal-title><trans-title-group xml:lang="ru"><trans-title>Сеченовский вестник</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2218-7332</issn><issn pub-type="epub">2658-3348</issn><publisher><publisher-name>Сеченовский Университет</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.47093/2218-7332.2020.11.2.87-91</article-id><article-id custom-type="elpub" pub-id-type="custom">sechenov-244</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>COVID-19</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>COVID-19</subject></subj-group></article-categories><title-group><article-title>Silent hypoxemia in a patient with severe SARS-CoV-2 pneumonia</article-title><trans-title-group xml:lang="ru"><trans-title>Немая гипоксемия у пациента с тяжелой SARS-CoV-2-пневмонией</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3665-4044</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пальман</surname><given-names>А. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Palman</surname><given-names>A. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пальман Александр Давидович, канд. мед. наук, доцент кафедры госпитальной терапии № 1 </p><p>ул. Трубецкая, д. 8, стр. 2, г. Москва, 119991</p></bio><bio xml:lang="en"><p>Alexander D. Palman, MD, PhD, Associate Professor, Department of Hospital Therapy No. 1</p><p>8/2, Trubetskaya str., Moscow, 119991</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0276-7374</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Андреев</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Andreev</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Андреев Денис Анатольевич, д-р мед. наук, профессор, зав. кафедрой кардиологии, функциональной и ультразвуковой диагностики </p><p>ул. Трубецкая, д. 8, стр. 2, г. Москва, 119991</p></bio><bio xml:lang="en"><p>Denis A. Andreev, MD, PhD, DMSc, Professor, Head of the Department of Cardiology, Functional and Ultrasound Diagnostics</p><p>8/2, Trubetskaya str., Moscow, 119991</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7792-0372</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сучкова</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Suchkova</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сучкова Светлана Александровна, врач-кардиолог кардиологического отделения для больных инфарктом миокарда Университетской клинической больницы № 1</p><p>ул. Трубецкая, д. 8, стр. 2, г. Москва, 119991</p></bio><bio xml:lang="en"><p>Svetlana A. Suchkova, cardiologist, Cardiology Department for patients with myocardial infarction, University Clinical Hospital No. 1</p><p>8/2, Trubetskaya str., Moscow, 119991</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский университет)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Sechenov First Moscow State Medical University (Sechenov University)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>06</day><month>12</month><year>2020</year></pub-date><volume>11</volume><issue>2</issue><issue-title>Special Issue: COVID-19</issue-title><fpage>87</fpage><lpage>91</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Palman A.D., Andreev D.A., Suchkova S.A., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Пальман А.Д., Андреев Д.А., Сучкова С.А.</copyright-holder><copyright-holder xml:lang="en">Palman A.D., Andreev D.A., Suchkova S.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.sechenovmedj.com/jour/article/view/244">https://www.sechenovmedj.com/jour/article/view/244</self-uri><abstract><p>Patients with COVID-19 are typically characterized by severe lung injury with the development of acute respiratory failure. However, in some patients, subjective well-being may remain relatively satisfactory for a long time and, despite severe hypoxemia, they do not complain of shortness of breath.</p><sec><title>Case report</title><p> Case report. We observed a 65-year-old man hospitalized with severe SARS-CoV-2 pneumonia, low level of blood oxygen saturation, but at the same time without complaints of shortness of breath. Only as the disease progressed with a decrease in oxygen saturation when breathing atmospheric air (SpO2 ) lower than 85% he began to notice a feeling of lack of air. The patient’s condition worsened and as a result, he died in the intensive care unit from multiple organ failure.</p></sec><sec><title>Discussion</title><p> Discussion. This case clearly illustrates one more feature of the course of pneumonia associated with the novel SARSCoV-2 coronavirus and shows that SpO2 measurement is one of the leading objective criterion that allows a doctor to assess the real severity of a patient’s condition with COVID-19.</p></sec></abstract><trans-abstract xml:lang="ru"><p>Для пациентов с COVID-19 характерно тяжелое поражение легких с развитием острой дыхательной недостаточности. Однако у части пациентов самочувствие может длительное время оставаться относительно удовлетворительным и, несмотря на выраженную гипоксемию, они не жалуются на одышку.</p><sec><title>Описание случая</title><p> Описание случая. Мы наблюдали 65-летнего мужчину, госпитализированного с тяжелой SARS-CoV-2-пневмонией, низкими показателями насыщения крови кислородом, но при этом без жалоб на одышку. Только при прогрессировании заболевания со снижением сатурации кислородом (SpO2 ) до 85% и ниже при дыхании атмосферным воздухом он стал отмечать чувство нехватки воздуха. Состояние пациента ухудшалось, и в итоге он скончался в отделении интенсивной терапии от полиорганной недостаточности.</p></sec><sec><title>Обсуждение</title><p> Обсуждение. Этот случай наглядно иллюстрирует еще одну особенность течения пневмонии, ассоциированной с новым коронавирусом SARS-CoV-2, и показывает, что измерение SpO2 является одним из ведущих объективных критериев, позволяющим врачу оценить реальную тяжесть состояния пациента с COVID-19.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID-19</kwd><kwd>SARS-CoV-2</kwd><kwd>острая дыхательная недостаточность</kwd><kwd>немая гипоксемия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID-19</kwd><kwd>SARS-CoV-2</kwd><kwd>acute respiratory failure</kwd><kwd>silent hypoxemia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Zhu N., Zhang D., Wang W., et al. A novel coronavirus from patients with pneumonia in China, 2019. 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