sechenovSechenov Medical JournalСеченовский вестник2218-73322658-3348Сеченовский Университетsechenov-48Research ArticleСтатьиTREATMENT OF RENAL ANEMIA: FROM BLOOD TRANSFUSIONS AND EXOGENOUS STIMULANTS OF ERYTHROPOIESISTO NEW PHYSIOLOGICAL APPROACHESЛЕЧЕНИЕ НЕФРОГЕННОЙ АНЕМИИ: ОТ ГЕМОТРАНСФУЗИЙ И ЭКЗОГЕННЫХ СТИМУЛЯТОРОВ ЭРИТРОПОЭЗА - К НОВЫМФИЗИОЛОГИЧЕСКИМ ПОДХОДАМАйтбаевК. А.AitbaevK. A.noemail@neicon.ruМуркамиловИ. Т.MurkamilovI. T.noemail@neicon.ruФоминВ. В.FominV. V.noemail@neicon.ruНаучно-исследовательский институт молекулярной биологии и медицины при Национальном центре кардиологии и терапии им. академика Мирсаида МиррахимоваРоссияNational Center of Cardiology and Therapy named after Academician Mirsaid MirrahimovRussian FederationКГМА им. И.К. Ахунбаева; Национальный центр кардиологии и терапии им. академика Мирсаида МиррахимоваРоссияNational Center of Cardiology and Therapy named after Academician Mirsaid MirrahimovRussian FederationФГАОУ ВО Первый МГМУ им. И.М. Сеченова (Сеченовский Университет)РоссияI.M. Sechenov First Moscow State Medical UniversityRussian Federation201830032018012833Copyright © Aitbaev K.A., Murkamilov I.T., Fomin V.V., 20182018Айтбаев К.А., Муркамилов И.Т., Фомин В.В.Aitbaev K.A., Murkamilov I.T., Fomin V.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.sechenovmedj.com/jour/article/view/48

The review presents new pharmaceuticals for the treatment of anemia in chronic kidney disease that have been developed in recent years and are currently in the clinical testing phase. Mechanisms of action, as well as potential side effects are examined. Based on the analysis of data from preliminary clinical trials, it is concluded that the new pharmaceuticals are highly effective and well tolerated by patients, and in the coming years, could be included in the therapeutic arsenal for treatment of nephrogenic anemia.

В обзоре представлены новые лекарственные препараты для лечения анемии при хронической болезни почек, которые разработаны в последние годы и находятся в настоящее время на стадии клинических испытаний. Рассмотрены механизмы их действия, а также потенциально возможные побочные эффекты при использовании. На основании анализа данных предварительных клинических исследований делается вывод, что новые лекарственные препараты обладают высокой эффективностью, хорошо переносятся больными и в ближайшие годы могут быть включены в арсенал терапевтических средств для лечения нефрогенной анемии.

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The authors declare that there are no conflicts of interest present.