sechenovSechenov Medical JournalСеченовский вестник2218-73322658-3348Сеченовский Университетsechenov-560Research ArticleTHE ACHIEVEMENTS OF PREVENTIVE MEDICINEДОСТИЖЕНИЯ ПРОФИЛАКТИЧЕСКОЙ МЕДИЦИНЫHISTORY AND TECHNOLOGICAL ASPECTS OF ANTIBIOTIC SENSITIVITY TESTINGИСТОРИКО-ТЕХНОЛОГИЧЕСКИЕ АСПЕКТЫ ОПРЕДЕЛЕНИЯ ЧУВСТВИТЕЛЬНОСТИ МИКРОБОВ К АНТИБИОТИКАМЗверевВ. В.ZverevV. V.

Доктор биологических наук, профессор, акад. РАН, заведующий кафедрой микробиологии, вирусологии и иммунологии Первого МГМУ имени И.М. Сеченова Минздрава России, директор НИИ вакцин и сывороток им. И.И. Мечникова РАН

Prof., Acad. RAS, head. Department of Microbiology, Virology and Immunology of the First Sechenov Moscow State Medical University, Director of Federal State Budgetary Scientific Institution I. Mechnikov RIVS

НесвижскийЮ. В.NesvizhskiyYu. V.

Несвижский Юрий Владимирович - доктор медицинских наук, профессор, декан медико-профилактического факультета

125009, Москва, ул. Моховая, д. 11, стр. 10 Телефон: + 7 903 557-50-51

Yuri Nesvizhskiy - Dr. med. Sciences, Professor, Dean, faculty of preventive medicine.

11, p. 10, Mokhovaya str., Moscow, 125009 Tel.: + 7 903 557-50-51

nesviz@mail.ruМиндлинС. Н.MindlinS. N.

Студент центра инновационных образовательных программ «Медицина Будущего»

Student of the center for innovative educational programs Medicine

ТарасоваН. Ю.TarasovaN. Yu.

Студентка центра инновационных образовательных программ «Медицина Будущего»

Futurethe First Sechenov Moscow State Medical University

Первый МГМУ имени И.М. Сеченова Минздрава России; НИИ вакцин и сывороток им. И.И. Мечникова, РАНРоссияFirst Sechenov Moscow State Medical University; Federal State Budgetary Scientific Institution I. Mechnikov Research Institute of Vaccines and SeraRussian FederationПервый МГМУ имени И.М. Сеченова Минздрава РоссииРоссияFirst Sechenov Moscow State Medical UniversityRussian Federation201630032016011218Copyright © Zverev V.V., Nesvizhskiy Y.V., Mindlin S.N., Tarasova N.Y., 20162016Зверев В.В., Несвижский Ю.В., Миндлин С.Н., Тарасова Н.Ю.Zverev V.V., Nesvizhskiy Y.V., Mindlin S.N., Tarasova N.Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.sechenovmedj.com/jour/article/view/560

The present article discusses a history and technological aspects of antibiotic susceptibility testing methods and indentifies individual periods associated with the introduction of new technologies. The article demonstrates that the introduction of a diagnostic approach is associated with technological elaboration, standardization, the availability of appropriate equipment, qualified personnel, organizational structure and the international recognition, as well as medical and economic efficiency. “Noncultural” automated technologies seem to be promising for practical implementation. Meanwhile, the progressin this field requires serious consideration of a number of technological and organizational issues, e.g. standardization and the proof of specificity.

В представленной статье дается историко-технологическая оценка развития методов определения чувствительности микробов к антибиотикам и показано наличие отдельных периодов, ассоциирующихся с внедрением определенных технологий. Показано, что внедрение того или иного диагностического подхода связано с его технологической проработанностью, стандартизованностью, наличием соответствующего оснащения, квалифицированных кадров, организационной структуры и международного признания, а также медицинской и экономической эффективности. Представляется перспективным внедрение в практику «некультуральных» автоматизированных технологий. Между тем, развитие этого направления диагностики требует серьезной проработки ряда технологических и организационных вопросов, одним из которых является стандартизация, а также доказательство специфичности.

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The authors declare that there are no conflicts of interest present.