sechenovSechenov Medical JournalСеченовский вестник2218-73322658-3348Сеченовский Университетsechenov-607Research ArticlePSYCHIATRY AND NARCOLOGYПСИХИАТРИЯ И НАРКОЛОГИЯA possible interconnection between the sensitivity to phenyltiokarbimid and alcohol dependenceВозможная взаимосвязь между чувствительностью к фенилтиокарбимиду и алкогольной зависимостьюМячинаО. В.MyachinaO. V.

к.м.н., ассистент кафедры биологии с экологией

PhD, assistant of the chair of biology with ecology

ЗуйковаА. А.ZuykovaA. A.

д.м.н., профессор, зав. кафедрой общей врачебной практики (семейной медицины)

MD, prof, head of chair of general medical practice (family medicine)

ПашковА. Н.PashkovA. N.

Александр Николаевич Пашков, д.б.н., профессор, заведующий кафедрой биологии с экологией

394036, Воронеж, Студенческая, 10, второй этаж, левое крыло Телефон: (4732) 53-04-13

prof., head of chair of biology with ecology

canc@vsma.ac.ruПоповС. Н.PopovS. N.

зам. главного врача по лечебной работе, ГУЗ «Воронежский областной психоневрологический диспансер»; научный сотрудник Воронежской государственной медицинской академии им. Н. Н. Бурденко

deputy doctor-in-chief of the Voronezh regional psychoneurological dispensary, lecturer

Воронежская государственная медицинская академия им. Н. Н. БурденкоРоссияVSMA named after N. N. BurdenkoRussian FederationГУЗ «Воронежский областной психоневрологический диспансер»; Воронежская государственная медицинская академия им. Н. Н. БурденкоРоссияVSMA named after N. N. BurdenkoRussian Federation20113003201101-23034Copyright © Myachina O.V., Zuykova A.A., Pashkov A.N., Popov S.N., 20112011Мячина О.В., Зуйкова А.А., Пашков А.Н., Попов С.Н.Myachina O.V., Zuykova A.A., Pashkov A.N., Popov S.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.sechenovmedj.com/jour/article/view/607

The aim of this research is to investigate the connection between sensitivity to phenyltiokarbimid (PHTK) and alcohol dependence. The determination of the sensitivity to PHTK is based on those methodes named after H. Harris and H. Kalmus (1949). The distribution of PHTK sensitivity is studied on the amount of 91 patients: 59 of them are with the diagnosis «moderate nonalcoholic syndrome», 33 of them are with the diagnosis «the syndrome of alcohol and delirium cancellation». The group of patients under consideration consisted of 29 healthy men. Statistically significant lowering of the threshold of taste sensitivity to PHTK is revealed. The conclusion is that a significant amount of non-sensitive patients who are alcohol dependent are found.

Цель исследования – изучение связи между вкусовой чувствительностью к фенилтиокарбамиду (ФТК) и алкогольной зависимостью. Определение сенситивности к ФТК проводилось методом H. Harris и H. Kalmus (1949). Изучено распределение чувствительности к ФТК у 91 пациента: 59 – с диагнозом «синдром отмены алкоголя средней тяжести» (СОА), 33 – с диагнозом «синдром отмены алкоголя с делирием» (СОАД). Контрольная группа состояла из 29 практически здоровых человек. Выявлено статистически достоверное снижение порога вкусовой чувствительности к ФТК и значительное количество нечувствительных среди лиц, страдающих алкоголизмом, по сравнению с практически здоровыми людьми.

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The authors declare that there are no conflicts of interest present.