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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">sechenov</journal-id><journal-title-group><journal-title xml:lang="en">Sechenov Medical Journal</journal-title><trans-title-group xml:lang="ru"><trans-title>Сеченовский вестник</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2218-7332</issn><issn pub-type="epub">2658-3348</issn><publisher><publisher-name>Сеченовский Университет</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">sechenov-62</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Сomparative analysis of respiratory support for endoscopic sleeve gastroplasty in patients with morbid obesity</article-title><trans-title-group xml:lang="ru"><trans-title>Сравнительный анализ режимов респираторной поддержки при эндоскопической гастропластике у больных с морбидным ожирением</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Неймарк</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Neimark</surname><given-names>M. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Киселев</surname><given-names>Р. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kiselev</surname><given-names>R. V.</given-names></name></name-alternatives><email xlink:type="simple">fincher-75@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО Алтайский государственный медицинский университет Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Altay State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>30</day><month>06</month><year>2018</year></pub-date><volume>0</volume><issue>2</issue><fpage>49</fpage><lpage>57</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Neimark M.I., Kiselev R.V., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Неймарк М.И., Киселев Р.В.</copyright-holder><copyright-holder xml:lang="en">Neimark M.I., Kiselev R.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.sechenovmedj.com/jour/article/view/62">https://www.sechenovmedj.com/jour/article/view/62</self-uri><abstract><p>For the analysis of the effect of respiratory support on the parameters of external respiration, gas exchange, peripheral and central hemodynamics in endoscopic sleeve gastroplasty in patients with morbid obesity a randomized study of 58 patients with morbid obesity was conducted, in which endoscopic sleeve gastroplasty was performed under combined anesthesia. Depending on the choice of the mode of pulmonary ventilation (PV), the patients were divided into two groups. In the 1st group (n = 28) patients had respiratory support in the volume-controlled ventilation mode (VCV); in the 2nd group (n = 30) they had respiratory support in the pressure-controlled ventilation (PCV) mode. The parameters of central hemodynamics, external respiration, peripheral hemodynamics, ABB were monitored intraoperatively. It was found that a significantly higher level of oxygenation was detected with PCV mode: PaO2 - 96.8 (92.7; 99.8) mm Hg, (PaO2/FiO2) 322.6 (341.2; 304.7) mm Hg in comparison with VCV mode: PaO2 - 92.2 (87.5; 96.3) mm Hg, PaO2/FiO2 - 307.3 (286.2; 331.7) mm Hg, and in second stage of the study (p &lt; 0,05).</p></abstract><trans-abstract xml:lang="ru"><p>Для анализа влияния режимов респираторной поддержки на параметры внешнего дыхания, газообмена, периферическую и центральную гемодинамику при эндоскопической гастропластики у больных с морбидным ожирением проведено рандомизированное исследование 58 пациентов с морбидным ожирением, которым была выполнена эндоскопическая гастропластика в условиях сочетанной анестезии. В зависимости от выбора режима искусственной вентиляции легких (ИВЛ) больные были разделены на две группы: в 1-й группе (n = 28) респираторная поддержка в режиме, контролируемом по объему (VCV); во 2-й группе (n = 30) респираторная поддержка в режиме, контролируемом по давлению (PCV). Интраоперационно мониторировали параметры центральной гемодинамики, внешнего дыхания, периферическую гемодинамику, кислотно-щелочное состояние (КЩС). Было выяснено, что при ИВЛ в режиме PCV выявлен достоверно более высокий уровень оксигенации: РаО2 - 96,8 (92,7; 99,8) мм рт. ст., РаО2/FiO2 - 322,6 (341,2; 304,7) мм рт. ст. - в сравнении с вентиляцией в режиме VCV: РаО2 - 92,2 (87,5; 96,3) мм рт. ст., РаО2/FiO2 - 307,3 (286,2; 331,7) мм рт. ст., так же начиная со 2-го этапа исследования (р &lt; 0,05).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>морбидное ожирение</kwd><kwd>респираторная поддержка</kwd><kwd>центральная гемодинамика</kwd><kwd>индекс оксигенации</kwd><kwd>карбоксиперитонеум</kwd></kwd-group><kwd-group xml:lang="en"><kwd>morbid obesity</kwd><kwd>respiratory support</kwd><kwd>central hemodynamics</kwd><kwd>oxygenation index</kwd><kwd>carboxyperitoneum</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Finucane MM, Stevens GA, Cowan M, Danaei G, Lin JK, Paciorek CJ, Singh GM, Gutierrez HR, Lu Y, Bahalim AN, Farzadfar F, Riley LM, Ezzati M. 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