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Mathematical modeling of macrophage reprogramming during inflammation and immunity processes: obstacles and opportunities

摘要

This mini-review is devoted to the problem of mathematical modeling of macrophage-related processes during inflammation and immunopatohological states, especially regarding the aspect of the modeling of gene expression modulatory mechanisms and macrophage reprogramming.

关于作者

V. Sakharov
I.M. Sechenov First MSMU
俄罗斯联邦


P. Litvitsky
I.M. Sechenov First MSMU
俄罗斯联邦


参考

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5. Zhou W. Mathematical modeling of MHC class II mediated immune responses in tissues (2010). Graduate Theses and Dissertations. Paper 11440. URL: http://www.lib.dr.iastate.edu/etd/11440 (дата обращения: 02.10.2014);

6. Wang Y., Yang T., Ma Y. Mathematical modeling and stability analysis of macrophage activation in left ventricular remodeling post-myocardial infarction // BMC Genomics. 2012. № 13 (Suppl 6):S21. 8 p. URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3481436/ (дата обращения: 11.10.2014);

7. Nedosekina E.A., Ananko E.A., Likhoshvai V.A. Cоnstruction of mathematical model of the gene network on macrophage activation under the action of IFN-γ and LPS // Bioinformatics of Genom Regulation and Structure. 2002. P. 156-159 URL: http://www.bionet.nsc.ru/meeting/bgrs_proceedings/papers/2002/BGRS_2002_2_046.pdf (дата обращения: 02.10.2014).


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ISSN 2218-7332 (Print)
ISSN 2658-3348 (Online)