Bioresorbable collagen materials in surgery: 50 years of success
A. L. Fayzullin,
A. B. Shekhter,
L. P. Istranov,
E. V. Istranova,
T. G. Rudenko,
A. E. Guller,
R. K. Aboyants,
P. S. Timashev,
D. V. Butnaru https://doi.org/10.47093/2218-7332.2020.11.1.59-70
Abstract
Collagen materials are widely applied in medicine due to optimal handling characteristics, biocompatibility, controlled biodegradation, the ability to form complexes with drugs and facilitate regeneration. Researchers from Sechenov University developed, studied in experiments and introduced into medicine a variety of materials based on collagen — a protein of connective tissue. At the same time, new collagen materials were launched into clinical practice abroad. In this review of Russian and world literature, we described how scientific and applied studies of collagen materials developed over time and tried to illustrate the current state and trends of collagen application for a variety of medical purposes — from hemostatic sponges to tissue-engineered constructs. The range of available collagen-based medical products and the emergence of new collagen materials indicate the keen interest in this biomaterial from the medical community and the potential of future discoveries.
About the Authors
A. L. Fayzullin
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Alexey L. Fayzullin, Junior research fellow, Institute for Regenerative Medicine
8/2, Trubetskaya str., Moscow, 119991
Tel.: +7 (917) 587-88-31
A. B. Shekhter
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Anatoly B. Shekhter, Professor, MD, PhD, DMSc, Head of the Laboratory of experimental morphology, Institute for Regenerative Medicine
8/2, Trubetskaya str., Moscow, 119991
L. P. Istranov
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Leonid P. Istranov, Professor, PhD, DSc, Principal research fellow, Institute for Regenerative Medicine
8/2, Trubetskaya str., Moscow, 119991
E. V. Istranova
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Elena V. Istranova, PhD, Leading research fellow, Institute for Regenerative Medicine
8/2, Trubetskaya str., Moscow, 119991
T. G. Rudenko
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Tatyana G. Rudenko, MD, PhD, Leading research fellow, Institute for Regenerative Medicine
8/2, Trubetskaya str., Moscow, 119991
A. E. Guller
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Anna E. Guller, PhD, Senior research fellow, Institute for Regenerative Medicine
8/2, Trubetskaya str., Moscow, 119991
R. K. Aboyants
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Ruben K. Aboyants, MD, PhD, engineer, Institute for Regenerative Medicine
8/2, Trubetskaya str., Moscow, 119991
P. S. Timashev
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Petr S. Timashev, PhD, DSc, Director, Institute for Regenerative Medicine
8/2, Trubetskaya str., Moscow, 119991
D. V. Butnaru
Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Denis V. Butnaru, MD, PhD, Vice-rector for Research and Public Relations
8/2, Trubetskaya str., Moscow, 119991
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