BONE METABOLISM AND EFFICACY OF THE ZOLEDRONIC ACID IN LOCALLY ADVANCED AND DISSEMINATED PROSTATE CANCER
Abstract
This article deals with the problem of bone metabolism in the case of locally advanced prostate cancer.
About the Authors
P. V. GlybochkoRussian Federation
P.V. Glybochko, MD, corresp. member of RAMS, prof., rector of the First MSMU named after I.M. Sechenov
Y. G. Alyaev
Russian Federation
Yu.G. Alyaev, MD, corresp. member of RAMS, prof., honored scientist of RF, director of the Research centre of uronephrology and reproductive health, head of the chair of urology of the First MSMU named after I.M. Sechenov
A. Z. Vinarov
Russian Federation
A.Z. Vinarov, MD, deputy director for scientifi c work of the Research centre of uronephrology and reproductive health, prof. of the chair of urology of the First MSMU named after I.M. Sechenov
Y. L. Demidko
Russian Federation
Yu.L. Demidko, MD, head of the cabinet of urodynamic diagnosis (University Hospital № 2)
O. V. Zelenova
Russian Federation
O.V. Zelenova, PhD, lecturer, head of the depot of the chair of organization of drug supply and pharmacoeconomics
References
1. Bruder J.M., Ma J.Z., Basler J.W., Welch M.D. Prevalence of osteopenia and osteoporosis by central and peripheral bone mineral density in men with prostate cancer during androgen-deprivation therapy // Urology. — 2006. — Vol. 67(1). — P. 152–155.
2. Preston D.M., Torréns J.I., Harding P., Howard R.S., Duncan W.E., McLeod D.G. Androgen deprivation in men with prostate cancer is associated with an increased rate of bone loss // Prostate Cancer Prostatic Dis. — 2002. — Vol. 5(4). — P. 304–310.
3. Моисеенко В.М. Паллиативное лечение больных солидными опухолями с метастатическим поражением костей. Лекции по фундаментальной и клинической онкологии. — СПб., 2004.
4. Orwoll E.S., Klein R.F. Osteoporosis in men // Endocr. Rev. — 1995. — Vol. 16(1). — P. 87–116.
5. Eastham J.A. Bone health in men receiving androgen deprivation therapy for prostate cancer // J. Urol. — 2007. — Vol. 177(1). — P. 17–24.
6. Percival R.C., Urwin G.H., Harris S., Yates A.J., Williams J.L., Beneton M., Kanis J.A. Biochemical and histological evidence that carcinoma of the prostate is associated with increased bone resorption // Eur. J. Surg. Oncol. — 1987. — Vol. 13(1). — P. 41–49.
7. Clarke N.W., McClure J., George N.J. Morphometric evidence for bone resorption and replacement in prostate cancer // Br. J. Urol. — 1991. — Vol. — 68(1). — P. 74–80.
8. Oefelein M.G., Ricchiuti V., Conrad W., Resnick M.I. Skeletal fractures negatively correlate with overall survival in men with prostate cancer // J. Urol. — 2002. — Vol. 168(3). — P. 1005–1007.