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Methotrexate in a psoriatic arthritis patient

摘要

The case report a psoriatic arthritis patient (disfiguring form, high laboratory values, changes of the skin and nails) treated with methotrexate. The drug demonstrated high efficacy resulting in stable sustained remission of articular syndrome, documented both by clinical and laboratory parameters, decreased cutaneous syndromes, improved functional activity and better life quality.

关于作者

K. Aleksanyan
I.M. Sechenov First Moscow State Medical University
俄罗斯联邦


E. Zholobova
I.M. Sechenov First Moscow State Medical University
俄罗斯联邦


S. Chebysheva
I.M. Sechenov First Moscow State Medical University
俄罗斯联邦


A. Meleshkina
I.M. Sechenov First Moscow State Medical University
俄罗斯联邦


M. Nikolaeva
University Child Clinic Hospital, Sechenov First Moscow State Medical University
俄罗斯联邦


参考

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2. Чебышева С.Н., Геппе Н.А., Подчерняева Н.С., Лыскина Г.А. (ред.). Псориатический артрит. Руководство по детской ревматологии. М.: ГЭОТАР-Медиа; 2011: 285–299.

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4. Veale D., Ritchlin С., FitzGerald О. Immunopathology of psoriasis and psoriatic arthritis. Ann. Rheum. Dis. 2005; 64(Suppl. II): 26–29.

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7. Tukova J., Chladek J., Nemcova D. et al. Methotrexate bioavailability after oral and subcutaneous administration in children with juvenile idiopathic arthritis. Clin. Exp. Rheumatol. 2009; 27(6): 1047–1053.

8. Alsufyani K., Ortiz-Alvarez O., Cabral D.A. et al. The role of subcutaneous administration of methotrexate in children with juvenile idiopathic arthritis who have failed oral methotrexate. J. Rheumatol. 2004; 31(1): 179–182.

9. Klein A., Kaul I., Foeldvari I., Ganser G., Urban A., Horneff G. Efficacy and safety of oral and parenteral methotrexate therapy in children with juvenile idiopathic arthritis: an observational study with patients from the German Methotrexate Registry. Arthritis Care Res. (Hoboken). 2012; 64(9): 1349–1356.


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ISSN 2218-7332 (Print)
ISSN 2658-3348 (Online)