RETRACTED: Anti-relapse chemotherapy in liver echinococcosis
摘要
Study objective – the effectiveness of clinical-based schemes of Albendazole anti-relapse chemotherapy. We studied the long-term results of surgical treatment of 709 patients with various forms of liver echinococcosis. Depending on the scheme of preventive treatment, the patients were divided into four groups. The fifth (control) group consisted of patients who did not receive anti-relapse chemotherapy with Albendazole. The recurrence frequency was evaluated by the survey 3–3,5 years after surgery. We found that Albendazole preventive treatment significantly reduces the relapse rate within 3–3,5 years after surgery. In the control group, relapse occurred in 42 cases (8,1%) (χ2 =10,6; р=0,0012), compared to 2 relapse cases in the study groups (1,1%). Aparasitic and antiparasitic regimes are necessary but not sufficient to prevent recurrence. The isolated relapse cases in various Albendazole preventive treatment schemes demonstrated no clear advantage of any scheme.
关于作者
A. Chernousov
I.M. Sechenov First MSMU
俄罗斯联邦
俄罗斯联邦
T. Mukantaev
Mangistau regional hospital
哈萨克斯坦
哈萨克斯坦
D. Vychuzhanin
I.M. Sechenov First MSMU
俄罗斯联邦
俄罗斯联邦
V. Levkin
I.M. Sechenov First MSMU
俄罗斯联邦
俄罗斯联邦
R. Nurutdinov
I.M. Sechenov First MSMU
俄罗斯联邦
俄罗斯联邦
参考
1. Ахмедов И.Г. Рецидив эхинококковой болезни: патогенетические аспекты, профилактика, ранняя диагностика и лечение. Хирургия. 2006; 4: 52–57.
2. Ахмедов И.Г., Курбанова А.И. Ранняя диагностика рецидива эхинококковой болезни. Хирургия. 2008; 11: 39–43.
3. Ахмедов Р.М., Мирходжаев И.А., Шарипов У.Б. и др. Миниинвазивные вмешательства при эхинококкозе печени. Анналы хирургической гепатологии. 2010; 15(3): 99–104.
4. Вафин А.З., Абдоков А.Д., Попов А.В., Хушвактов У.Ш. Клиническая эффективность применения принципа апаразитарности и антипаразитарности в хирургии эхинококкоза. Медицинский вестник Северного Кавказа. 2010; 2: 10–13.
5. Arif S.H., Shams-Ul-Bari N.A., Wani N.A., Zargar S.A., Wani M.A., Tabassum R., Hussain Z., Baba A.A., Lone R.A. Albendazole as an adjuvant to the standard surgical management of hydatid cyst liver. Int. J. Surg. 2008; Dec; 6(6): 448–51.
6. Bildik N., Cevik A., Altintaş M., Ekinci H., Canberk M., Gülmen M. Efficacy of preoperative albendazole use according to months in hydatid cyst of the liver. J. Clin. Gastroenterol. 2007. Mar; 41(3): 312–316.
7. Gomez I., Gavara C., López-Andújar R., Belda Ibáñez T., Ramia Ángel J.M., Moya Herraiz Á., Orbis Castellanos F., Pareja Ibars E., San Juan Rodríguez F. Review of the treatment of liver hydatid cysts. World J. Gastroenterol. 2015; Jan 7; 21(1): 124–131.
8. Hadzhiev B., Todorov A., Sakakushev B., Atanasov B. [Surgical treatment of hepatic echinococcosis-10-year experience]. [Article in Bulgarian]. Khirurgiia (Sofiia). 2011; 3: 76–79.
9. Polat K.Y., Balik A.A., Oren D. Percutaneous drainage of hydatid cyst of the liver: long-term results. HPB (Oxford). 2002; 4(4): 163–166.
10. Rajesh R., Dalip D.S., Anupam J., Jaisiram A. Effectiveness of puncture-aspiration-injection-reaspiration in the treatment of hepatic hydatid cysts. Iran J. Radiol. 2013; Jun; 10(2): 68–73.
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