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Anticoagulant therapy control in primary healthcare setting

Abstract

The aim of the study was to evaluate efficiency anticoagulant therapy control in primary healthcare setting. The prospective, controlled study involved 301 patients with «non-valvular» atrial fibrillation, receiving various anticoagulant drugs in 2013–2015. After discharge the patients were advised to visit anticoagulant therapy control department. The risk of thromboembolic complications and the risk of bleeding  were assessed with CHA2DS2VASc scale HAS-BLED, respectively. Major bleeding was assessed with TIMI scale. The time in therapeutic range for Warfarin  was assessed for the patient taking warfarin. The study involved 301 patients with non-valvular atrial fibrillation taking anticoagulants: warfarin – 49 (16%), rivaroxaban – 34 (11%), apixaban – 81 (28%) and dabigatran –137 (45%). Minor bleeding was found in all groups. Large bleeding was found in patients receiving warfarin, dabigatran and rivaroxaban.

About the Authors

Z. K. Salpagarova
I.M. Sechenov First MSMU
Russian Federation

Zukhra K. Salpagarova - Postgraduate Student at the Department of Preventive and Urgent Cardiology, I.M. Sechenov First MSMU.

8/2, Trubetckaya str., Moscow, 119991

Tel.: +7 (499) 248-73-89, +7 (928) 382-99-99



D. A. Andreev
I.M. Sechenov First MSMU
Russian Federation

Doctor of Medical Science, Professor with the Department of Preventive and Urgent Cardiology, I.M. Sechenov First MSMU

8/2, Trubetckaya str., Moscow, 119991



D. A. Sichev
Russian Medical Academy of Post-Graduate Education
Russian Federation

Head of the Department of Clinical Pharmacology and Therapy, Russian Medical Academy of Post-Graduate Education.



A. A. Bikova
I.M. Sechenov First MSMU
Russian Federation

Assistant Professor with the Department of Preventive and Urgent Cardiology, I.M. Sechenov First MSMU.

8/2, Trubetckaya str., Moscow, 119991



S. A. Syrkin
I.M. Sechenov First MSMU
Russian Federation

Doctor of Medical Science, Professor, Head of the Department of Preventive and Urgent Cardiology, I.M. Sechenov First MSMU.

8/2, Trubetckaya str., Moscow, 119991



S. A. Suchkova
I.M. Sechenov First MSMU
Russian Federation

Postgraduate Student at the Department of Preventive and Urgent Cardiology, I.M. Sechenov First MSMU.

8/2, Trubetckaya str., Moscow, 119991



References

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6. Healey J.S., Eikelboom J., Douketis J. et al. Periprocedural bleeding and thromboembolic events with dabigatran compared with warfarin: results from the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) randomized trial. Circulation. 2012; 126 (3): 343–348.


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ISSN 2218-7332 (Print)
ISSN 2658-3348 (Online)