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Epithelial reticular cells of the thymus and the regulatory T-lymphocytes

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The article presents a review of the literature. The article presents the published data on the role of reticular epithelial cells in the formation of specific microenvironment in the cortex and medulla of thymic lobules. Thymic microenvironment plays a key role in T-cell differentiation. Discusses the role of medullar epithelial cells in the development of regulatory T-lymphocytes and induction of tolerance.

About the Authors

V. E. Torbek
I.M. Sechenov First MSMU
Russian Federation

Viktoriya Eduardovna Torbek, prof. of the chair of histology, cytology and embryology

6 Akad. Bakulev str., Moscow, 117513

Tel.: 8 (495) 629–75–69

S. L. Kuznetsov
I.M. Sechenov First MSMU
Russian Federation

MD, prof., head of the chair of histology, cytology and embryology


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