The investigation of kinetics dissolution of prolonged indapamide drugs in biorelevant media
Abstract
In the current work there was performed the development of the method of determination dissolution kinetics in biorelevant media of slightly soluble substance, for example indapamide. The method was validated in terms of specificity, linearity, precision, accuracy, analytical range. The method was applied to dissolution kinetic studies of extended-release indapamide preparations.
About the Authors
E. Yu. Sannikova
The First MSMU named after I.M. Sechenov
Russian Federation
Russian Federation
post-graduate student of the chair of pharmaceutical and toxicological chemistry
A. A. Kruglyakova
The First MSMU named after I.M. Sechenov
Russian Federation
Russian Federation
post-graduate student of the chair of pharmaceutical and toxicological chemistry
I. E. Shokhin
The First MSMU named after I.M. Sechenov
Russian Federation
Russian Federation
PhD, assistant of the chair of pharmaceutical and toxicological chemistry
G. V. Ramenskaya
The First MSMU named after I.M. Sechenov
Russian Federation
Russian Federation
Doctor of pharmacy, prof., head of the chair of pharmaceutical and toxicological chemistry, director of the Research institute of pharmacy
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