Regenerative medicine and dentistry (Review)
Abstract
The review goal. to analyze the prospects of regenerative medicine in dentistry Materials. Repin V.S., Rzhaninova A.A., Shamenkov D.A. “Embryonic stem cells: fundamental biology and medicine” (Moscow, 2002), relevant papers from PubMed (MeSH). Conclusion. Regenerative medicine is one of promising areas of modern medicine: in dentistry, for example, various stem cells (e.g., stem cells of bone marrow, stem cells of adipose tissue, and others) can be used to regenerate tissue defects. Moreover, dental stem cells (e.g., dental pulp stem cells, stem cells from human exfoliated deciduous teeth, stem cells from apical papilla) can be used to regenerate nervous tissue, myocardium, cartilages, liver, pancreas. The antiviral therapy with third molars stem cells can prevent cell malignization, in particular hepatic cells. However it is necessary to keep in mind possible adverse effect of regenerative treatment itself.
About the Authors
D. E. Suetenkov
Saratov State Medical University
Russian Federation
Russian Federation
A. P. Petrova
ФГБОУ ВО Саратовский ГМУ имени В.И. Разумовского Минздрава России
Russian Federation
Russian Federation
K. U. Zobnin
Saratov State Medical University
Russian Federation
Russian Federation
T. N. Zhevak
I.M. Sechenov First MSMU (Sechenov University)
Russian Federation
Russian Federation
References
1. Репин B.C., Ржанинова А.А., Шаменков Д.А. Эмбриональные стволовые клетки: фундаментальная биология и медицина. М.: Реметэкс; 2002: 175
2. Xiao L., Nasu M. From regenerative dentistry to regenerative medicine: progress, challenges, and potential applications of oral stem cells. Stem Cells and Cloning: Advances and Applications. 2014; 7: 89-99
3. Potdar P.D., Jethmalani Y.D. Human dental pulp stem cells: Applications in future regenerative medicine. World J. Stem Cells. 2015; 7(5): 839-851
4. Bakopoulou A., About I. Stem cells of dental origin: Current research trends and key milestones towards clinical application. Stem Cells International. 2016. Available at: http://dx.doi.org/10.1155/2016/4209891 (accessed March 15, 2017)
5. Narang S., Sehgal N. Stem cells: A potential regenerative future in dentistry. Indian J. Hum. Genet. 2012; May-Aug; 18(2): 150-154
6. Bassir S.H., Wisitrasameewong W., Raanan J. et al. Potential for stem cell-based periodontal therapy. J. Cell. Physiol. 2016; 231: 50-61
7. Maxim M.A., Soritau O., Baciut M. et al. The role of dental stem cells in regeneration. Clujul. Medical. 2015; 88(4): 479-482
8. Ashri N.Y., Ajlan S.A., Aldahmash A.M. Dental pulp stem cells. Biology and use for periodontal tissue engineering. Saudi Med. J. 2015; 36(12): 1391-1399
9. Han J., Menicanin D., Gronthos S., Bartold P.M. Stem cells, tissue engineering and periodontal regeneration. Australian Dental J. 2014; 59(1): 117-130
10. Ikeda E., Morita R., Nakao K. et al. Fully functional bioengineered tooth replacement as an organ replacement therapy. Proc. Natl. Acad. Sci. USA. 2009; 106(32): 13475-13480
11. Tatullo M., Marrelli M., Paduano F. The regenerative medicine in oral and maxillofacial surgery: The most important innovations in the clinical application of mesenchymal stem cells. Int. J. Med. Sci. 2015; 12(1): 72-77
12. Грудянов А.И., Сысоева В.Ю., Терновой Ю.В. Стволовые клетки и возможности их применения в пародонтологии. Стоматология. 2012; 1(1): 18-29
13. Kim J.-Y., Kim M.-R., Kim S.-J. Modulation of osteoblastic/odontoblastic differentiation of adult mesenchymal stem cells through gene introduction: A brief review. J. Korean Assoc. Oral Maxillofac. Surg. 2013; 39: 55-62
14. Liu J., Yu F., Sun Y. et al. Concise reviews: Characteristics and potential applications of human dental tissue-derived mesenchymal stem cells. Stem cells. 2015; 33: 627-638
15. Perez-Silos V., Camacho-Morales A., Fuentes-Mera L. Mesenchymal stem cells subpopulations: Application for orthopedic regenerative medicine. Stem Cells International. 2016. Available at: http://dx.doi.org/10.1155/2016/3187491 (accessed March 15, 2017)
16. Fawzy El-Sayed K.M., Dorfer Ch.E. Gingival Mesenchymal Stem/Progenitor Cells: A Unique Tissue Engineering Gem. Stem Cells International. 2016. Available at: http://dx.doi.org/10.1155/2016/7154327 (accessed March 15, 2017)
17. Somani R., Jaidka Sh., Bajaj N., Arorad S. Miracle cells for natural dentistry: A review. J. Oral Biol. Craniofac. Res. 2017; Jan-Apr; 7(1): 49-53
Review
Views: 325
Email this article 