The stress induced hyperglycemia of pathophysiologycal significance in stroke patients
Abstract
Stress induced hyperglycemia is a transient increase glucose blood level during the acute phase of ischemic stroke. Hyperglycemia enhances initiated by cerebral ischemia neuronal death, blood-brain barrier destruction, leads to hemorrhagic transformation, promotes the formation of brain edema. This increases the size of ischemic penumbra and increases the severity of neurological deficit. Stress hyperglycemia as a consequence of stress-realizing system activation is a significant pathogenetic link in ischemic stroke patients.
About the Authors
P. F. Litvitsky
I.M. Sechenov First MSMU
Russian Federation
Russian Federation
MD, prof., head of the chair of pathophysiology
N. F. Nuralieva
I.M. Sechenov First MSMU
Russian Federation
Russian Federation
the 5-th year student of the therapeutical faculty
S. P. Sergeeva
I.M. Sechenov First MSMU
Russian Federation
Russian Federation
Svetlana Pavlovna Sergeeva, PhD, associate prof. of the chair of pathophysiology
8–2 Trubetskaya str., Moscow, 119992
8 (917) 552–33–48
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