Перспективы генетического программирования Т-клеток в адоптивной иммунотерапии злокачественных новообразований
Аннотация
В статье представлен обзор литературы, раскрывающий основные аспекты и области применения адоптивной Т-клеточной терапии злокачественных новообразований. Адоптивный Т-клеточный перенос позволяет излечивать метастатическую болезнь на поздних этапах прогрессирования некоторых опухолей, обладая рядом преимуществ по сравнению с классической противоопухолевой терапией. Особое внимание в обзоре уделяется возможности генетического программирования адоптивных клеток, которое повышает эффективность и безопасность лечения больных онкологического профиля. Кроме этого, рассматриваются основные проблемы введения данного метода в повседневную клиническую практику.
Об авторах
О. Л. Морозова
ФГБОУ ВО Первый МГМУ имени И.М. Сеченова Минздрава России
Россия
Россия
Морозова Ольга Леонидовна, Доктор медицинских наук, профессор кафедры патофизиологии
119991, г. Москва, ул. Трубецкая, д. 8, стр. 2
В. В. Яковлев
ФГБОУ ВО Первый МГМУ имени И.М. Сеченова Минздрава России
Россия
Россия
Студент 3-го курса лечебного факультета
Н. А. Сушенцев
ФГБОУ ВО Первый МГМУ имени И.М. Сеченова Минздрава России
Россия
Россия
Студент 3-го курса лечебного факультета
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