DEVELOPMENT OF TECHNOLOGY FOR DRY EXTRACT PRODUCTION FROM JERUSALEM ARTICHOKE TUBERS
Abstract
The article dwells upon the technology of dry extract production from Jerusalem artichoke tubers. The most promising technology is maceration with stirring in 20% ethanol as an extractive solvent. the TLC method was used to identify the major active agents, polysaccharides content was determined spectrophotometrically. The obtained dry extract looks promising as an active substance for a drug formulation development.
About the Authors
Sh. S. RamazoniRussian Federation
Postgraduate
N. V. Chebishev
Russian Federation
Doctor biologie Sciences, Acad. RAE, professor of department of pharmaceutical technology of medicines Institute pharmacy technology Institute
L. A. Pavlova
Russian Federation
Lyudmila Pavlova - K. Pharm. Sciences. associate Professor, head. laboratory development and preclinical testing of medicines Institute pharmacy technology Institute.
P. 8, bld.2, Trubetskaya str., Moscow, 119991 Tel.: + 7 (495) 609-14-00 (* 3020)
N. B. Demina
Russian Federation
Doctor pharmaceutical Sciences, professor, professor of department of pharmaceutical technology of medicines Institute pharmacy technology Institute
D. M. Popov
Russian Federation
Doctor pharmaceutical Sciences, professor
D. R. Khalifaev
Russian Federation
Doctor pharmaceutical Sciences, professor, professor of department of pharmaceutical technology
References
1. Zelenkov V.N. Biomedical properties of a concentrate of Jerusalem artichoke (dried) and experience of using dietary SUPPLEMENTS on its basis in medical practice / V.N. Zelenkov // Actual problems of creation of new medicinal preparations of plant origin. Materials of the 4th Intern. Congress June 29 – July 1, 2000. Led. Novgorod, 2000. Pp. 158-163.
2. Beletskaya O.A. Biologically active food Supplement is a concentrate of Jerusalem artichoke in prevention and rehabilitation : immunotherapy in frequently and chronically ill children, patients with insulin-dependent diabetes mellitus and patients with post-States / E.A. Zhuk, V.A. Golino and others // human Ecology: food technology and products on the threshold of XXI century : proc. Dokl. The V Intern. Symposium. 18-21 Sept. 1997. M. Pyatigorsk. Pp. 43-45.
3. Akanov A.B. Correction of the Jerusalem artichoke to the level of blood glucose in rats with alloxan diabetes / D.D. Mukhambetov, A.B. Ahmadieva etc. // Man and medicine : abstracts. Dokl. 5 ROS. NAT. congruence. 2125 APR. 1998. M. 1998. S. 342.
4. Kisieva M.T. The Selection of the extraction conditions of pectin from tubers of Jerusalem artichoke (Helianthus tuberosus L.) using enzyme preparation Maksim NNP K / M.T Kisieva., N.C. Zyablitseva, V.A. Komantsev and others // Bulletin PFUR. Series: Medicine. 2010; No. 4: 237-239.
5. Ramazani Sh.S. The Development of complex technology of obtaining dry extract from Jerusalem artichoke tubers / Sh.S. Ramazani, D.R. Khalifaev, L.A. Pavlova, D.M. Popov // The Contribution of medical science to the improvement of the family : proceedings of the 63rd scientific and practical conference with international participation Dushanbe. 2015. Pp. 130-131.
6. Jerusalem artichoke tubers fresh. Helianthus tuberosus. FS RT 23-0004-15.- 17 04.- 2015.
7. Safarzoda R.Sh. Obtaining and standardization of homeopathic matrix tinctures of fresh tubers of Jerusalem artichoke / R.Sh. Safarzoda, D.R. Khalifaev, D.M. Popov // Modern aspects of the use of vegetable raw materials and raw materials of natural origin in medicine : proc. Dokl. 3rd scientific.-practical. Conf. Moscow. 2015.