Dynamics of proinflammatory cytokines level in stable angina (II–III functional class)
Abstract
The article discusses the evaluation of cytokine level (IL-1β, IL-6) in patients with II–III functional class stable angina. In the group of patients with II–III class stable angina, the standard therapy failed to normalize the level of proinflammatory cytokines IL-1β and IL-6. In the group of patients with II–III class stable angina when the standard therapy combined with TES-therapy significantly reduced level of proinflammatory cytokines (IL-1β, IL6). TES-therapy decreases painful systemic inflammatory response more effectively than the standard therapy thus preventing damaging effect of proinflammatory cytokines. TES therapy produces a homeostatic effect, restores the balance of pro – and anti-inflammatory cytokines. We recommend to include TES-therapy in the standard treatment program in II–III class stable angina patients.
About the Authors
E. K. Gordeeva
Kuban State Medical University
Russian Federation
Russian Federation
Elena Gordeeva, postgraduate student at the Department of General and Clinical Pathophysiology
4, Sedina str., Krasnodar, Russia, 350063
A. H. Kade
Kuban State Medical University
Russian Federation
Russian Federation
Doctor of Medical Sciences, Professor, Head of the Department of General and Clinical Pathophysiology
S. A. Zanin
Kuban State Medical University
Russian Federation
Russian Federation
Candidate of Medical Sciences, Аssistant Professor at the Department of General and Clinical Pathophysiology
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