Sechenov Medical Journal

Advanced search

Applications of snowdrop medicinal plant material in homeopathic pharmacy: a brief historical background and a systematic review of homeopathic medicines standardization

Full Text:


Currently, relevant studies are related to the development of private pharmacopeia articles with the requirements for medicinal plant raw materials and homeopathic mother tincture used in homeopathic practice. The article presents a brief overview of the history of the use of snowdrop in the offi cial allopathic and homeopathic medicine. Some aspects of standardization of medicinal plants and tinctures of homoeopathic matrix of Voronov snowdrop (Galanthus woronowii Losinsk) and Galanthus nivalis.

About the Authors

D. O. Bokov
I.M. Sechenov First MSMU
Russian Federation

Dmitry Olegovich Bokov, post-graduate of the chair of pharmacognosy

45 Nakhimovsky ave., Moscow, 117418

Tel.: 8 (499) 128–57–66

I. A. Samylina
I.M. Sechenov First MSMU
Russian Federation

Doctor of pharmacy, corresp. member of RAS, prof., head of the chair of pharmacognosy


1. Heinrich M., Teoh H.L. Galanthamine from snowdropthe development of a modern drug against Alzheimer’s disease from local Caucasian knowledge // Journal of Ethnopharmacology. 2004; 92: 147-162.

2. Mashkovsky M.D., Kruglikova-Lvova R.N. To pharmacology of new alkaloid galantamine // Farmakologiya i toksikologiya. 1951; 14(6): 27.

3. Mashkovsky M.D. Effect of galantamine on the sensitivity of skeletal muscle to acetylcholine // Farmakologiya i toksikologiya. 1955; 18(4): 21-27.

4. Proskurnina N.F., Yakovleva A.P. About alkaloids Galanthus woronowii II. Allocating a new alkaloid // Zhurnal obshchej khimii. 1952; 10(22): 1899.

5. Kalashnikov I.D. Research Galanthus nivalis, which grows in the western regions of the USSR, as a source of galantamine. PhD diss. abstract. 1970: 20.

6. Ivanova L.B. Phytochemical research of Galanthus nivalis var. gracilis // Farmatsiya (Bulgaria). 1957; 2(23).

7. Homoepathic Pharmacopoeia of the United States. Revision Service. Vol. 1: December 1988 – December 1990; Vol. 2: December 1989 – June 1990.

8. Order of the Ministry of Health of the Russian Federation № 335 MP from 11.29.95 «On the use of the homeopathic method in practical public health».

9. OFS Draft «Homeopathic tinctures and liquid matrix dilutions». Tincturae homoeopathicae maternae et liquoris dilutione.

10. Bokov D.O., Samylina I.A. Modern aspects of homeopathy in some herbs (family Amaryllidaceae, Trilliaceae) of central Russia in the treatment of neurological disorders. Homeopathic yearbook. Collected materials of the XXV-th Moscow International Homeopathic Conference «Development of Homeopathic Method In Modern Medicine» (January 23-24, 2015). M. «Moscow homeopathic center». 2015: 180-183.

11. Bokov D.O., Samylina I.A. Homeopathic remedies of snowdrops: key aspects for standardization procedures. Proceedings of the V International scientific-practical conference «Fundamental science and technology – promising developments» (24-25 February 2015). North Charleston, USA // Pharmaceutical sciences. 2015; 2: 184-186.

12. Zwitserse Apotheek [Electronic resource]. Galanthus Nivalis – UNDA-BOIRON. URL: https://www.

13. (accessed: 14.03.2015).

14. Washington Homeopathic Products [Electronic resource]. Galanthus Nivalis – Pills. URL: (accessed: 15.03.2015).

15. Helios Homoeopathy [Electronic resource]. Snowdrop. URL: (accessed: 15.03.2015).

16. Artyushenko Z.T. Amaryllidaceae (Amaryllidaceae Jaume St.-Hilaire) in USSR. Morphology, systematics and use. AS USSR. Botan. Inst. named after V.L. Komarov. L. «Nauka». 1970: 41-83.

17. Bokov D.O., Samylina I.A. Current status and future prospects of research of pharmacognostic representatives of subclass Liliidy (Liliidae) // Innovations in medicine and pharmacy – 2014: Materials of the remote scientificpractical Conf. of students and young scientists (November 11, 2014). Minsk. BSMU. 2014: 503-507.

18. Bokov D.O. The study based on the standardization of preparations representatives of Amaryllidaceae, looking for pharmacological regulation of neurodegenerative diseases and migraine // Materials of final All-Russian scientific and practical activities «Relay of university science – 2014» III Youth Medical Forum «MedWAYS – promising research areas – 2014» (December 4-5, 2014). M. Publishing House of the I.M. Sechenov First MSMU. 2014: 102.

19. Samylina I.A. et al. Scientific approaches to the development of common pharmacopoeia articles on homeopathic medicinal forms // Farmatsiya. 2010; 3: 53-56.

20. Kostennikova Z.P., Akashkina L.V. Analysis and standardization of homeopathic herbal medicines // Farmatsiya. 1993; 6: 59-62.

21. Kopytko Ya.F., Sokolskaya T.A., Dargaeva T.D. Regulation of the quality of homeopathic matrix tinctures and raw materials for their production in Russia and abroad // Traditsionnaya meditsina. 2010; 23: 53-56.

22. Shikh E.V. et al. On homeopathic medicinal products permitted for medical use in the Russian Federation // Vedomosti Nauchnogo tsentra ekspertizy sredstv meditsinskogo primeneniya. 2014; 4: 50-54.

23. Sakanyan E.I. et al. Medicinal forms and their place in the modern homeopathic practice // Vedomosti Nauchnogo tsentra ekspertizy sredstv meditsinskogo primeneniya. 2014; 2: 60-63.

24. Sokolskaya T.A. et al. Modern aspects of the development and standardization of homeopathic drugs // Zhurnal o rossij skom rynke lekarstv i meditsinskoj tekhnike. 2008; 12: 27-29.

25. Bulaev V.M., Chichenkov O.N. The quality problems and the therapeutic efficacy of homeopathic medicines authorized for use in the Russian Federation // Lekarstvennye preparaty i ratsionalnaya farmakoterapiya. 2013; 1: 33-38.

26. Zamarenov N.A. et al. Modern problems of homeopathy and its solutions. System to ensure the quality of homeopathic technology // Traditsionnaya meditsina. 2012; 31(29): 25-29.

27. Pyatigorskaya N.V. et al. Modern requirements for the production of homeopathic medicines // Traditsionnaya meditsina. 2010; 20: 8-13.


Views: 108

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.

ISSN 2218-7332 (Print)
ISSN 2658-3348 (Online)