RETRACTED: EVIDENCE OF ANCIENT HIV-1 TRANSMISSION IN THE NORTHERN EUROPE. PALAEOEPIDEMIOLOGICAL ANALYSIS
Abstract
Longitudinal co-evolution of human beings and pathogens resulted in polymorphism of Homo sapiens. CCR5Δ32 HIV-resistance allele is the exception to the rules. Recent origin of HIV-1 in Africa contradicted with the appearance of CCR5Δ32 allele in Northern Europe in previous ages. The author proposed non-contradictory theory of primary appearance of ancient HIV-1 in the Northern Europe 7–10 thousand years ago. The primary epidemics of HIV-infection had been stopped by the appearance of CCR5Δ32 mutation among the affected population. Reemergence of HIV-1 nowadays resulted by the penetration of hibernated HIV-1 into population of drug addicts and men having sex with men.
About the Author
V. P. Sergiev
The I.M. Sechenov First MSMU
Russian Federation
Russian Federation
Vladimir Petrovich Sergiev, MD, academician of RAMS, prof., head of the chair of tropical medicine and parasitic diseases, director of the Research Institute of medical parasitology and tropical medicine named after E.I. Martsinovsky
20 M. Pirogovskaya str., Moscow, 119435
Tel.: 8 (499) 246–80–49
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