Sechenov Medical Journal

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No 4 (2012)
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4-6 55

The participation of students and professors of the medical faculty of Moscow University in the war of 1812 is described in this article.

7-20 58

The paper gives a brief outline of the institutional and cognitive structure of university education and science in Russia as an example of the morphological sciences at the medical faculty of the Imperial Moscow University. The contribution to the development of histology of the Imperial Moscow University professors — P.P. Einbrodt (Jr.), I.M.Sokolov, J.A. Borzenkova is analyzed. The authors examined the original documents on the history of the Physiological Institute (cabinet) at the Department of Physiology, healthy person (or rather — histological Cabinet department of histology, embryology and comparative anatomy) of the Medical Faculty of IMU.


21-27 103

The ECG dispersion mapping method is a relatively new method for diagnosing the state of myocardium. It is based on a computer rendering of the electrical microalternations of ECG signal assigned to specific parts of the heart (two atria, two ventricles). Dispersive mapping method can be used in all areas of medicine that require early diagnosis and detection of changes and disorders of electrophysiological properties of myocardium. This paper describes the technical aspects of this method, as well as its use.


28-33 27

The purpose of this research is the identification of new etiopathogenetic, diagnostic and prognostic data of erosive forms of gastroesophageal reflux disease. The total number of examined is 40 patients with erosive form of the illness and 60 with nonerosive, 30 patients with chronic gastritis and 20 are practically healthy. Erosive and nonerosive forms of the disease have similar pathogenetic variants, but having substantial quantitative differences in the parameters of diffuse neuroendocrine system and indicators of cellular renovation of epitheliocytes, top floor digestive tract indicators of proliferation causes the appearance and progression of erosive-ulcerous of defeats in the upper part of digestive tract. 


34-38 187

Magnesium — intracellular cation — is important in many pathological processes including the pathogenesis of migraine. Magnesium deficiency in patients with migraine may be developed as a result of genetic inability to absorb magnesium and its excessive loss with stress because of low nutritional intake and a number of other reasons. Migraine magnesium deficiency contributes in changing the activity of NMDA-receptors, distribution of cortical depression hyperaggregation platelets, affects the function of serotonin receptors and metabolism of many neurotransmitters. Intravenous magnesium-containing drugs show high efficacy in the treatment and prevention of migraine.


39-45 35

The use of gas chromatography and mass spectrometry in the laboratory diagnostics of syphilis is described. The data of the indication of syphilitic lesions on the basis of identification of molecular markers are presented in this paper.


46-51 35

Since 2004 the incidence of hepatitis A of conscripts declined by more than 70 times, which happened primarily due to vaccination. The paper under review presents the characteristics of a phased strategy of specific prevention of hepatitis A, provides the comparative analysis of the immunological and epidemiological effectiveness of domestic (HEP-A-in-VAC) and foreign vaccines. Showing low reactogenicity and immunogenicity of an improved high enough vaccine HEP-A-in-VAC.


52-55 41

The aim of the study was to determine the degree of contamination of three kinds of female mosquitoes (Culex, Aedes, Anopheles) in some areas of Moscow and Nizhny Novgorod regions at different times of the warm season of the year (from May to September). Examined adult female mosquitoes collected in the Moscow and Nizhny Novgorod region in the summer of 2010 as potential vectors of Dirofilaria immitis and Dirofilaria repens. The presence of Dirofilaria spp. was detected by polymerase chain reaction using species-specific primers for D. immitis and D. repens. The index of Minimum Field Infection Rates (MFIR) was calculated.
It was founded that the MFIR ranged from 7 prob/1554 total mosquitoes (4,5) to 30 samples (19,3) of PCRpositive mosquitoes for D. immitis and D. repens, respectively. Dual infection with a D. Immitis, and D. repens was detected by PCR in 4 samples (2.6). The proximity of the area to Moscow increased the probability of detection of D. repens and in remote areas, on the contrary, was dominated by D. immitis. The highest rates of total infected mosquitoes were observed in early June and late August.
Concluded that the period of the most massive female mosquitoes infected from sick carnivores is at the beginning of August, the greatest risk of infection for healthy people and animals is in the late August — early September.

56-58 80

The present study reports one case 43-year-old male patient, living in an opistorchiasis endemic area. The patient had splenectomia after traumatic rupture of spleen 32 years ago. The clinical symptoms were fever, hepatomegaly, hyperleucocytosis, hypereosinophilia. The serological tests with parasitic and infectious diseases were negative. Abdominal ultrasound and CT revealed 2–3 cm focuses in hepatic parenchyma, diagnosed as metastatics. Diagnostic laparotomy, biopsy and morphology investigation revealed cholangiohepatitis, eosinophilia and step by step necrosis of hepatic parenchyma. The diagnosis of opistorchiasis was established 2 month later by serological test with antigen O. felineus. Clinical diagnosis was superinvasive opistorchiasis. The recovery after treatment with biltricide. The causes of peculiarity and seriously cours of disease and difficulty of diagnosis was discussed.

59-61 31

This article deals with the problems of parasitic diseases, with the analysis of epidemiological features of toxoplasmosis in Azerbaijan.


62-69 32


The problems of classification and anatomy of small glands located in the walls of organs of the digestive, respiratory, and urogenital systems. Shows the imperfection of the terminology used in describing the glands suggested to use terms related to their design. New data on the patterns of pre- and postnatal morphogenesis, design, structure and function relationships, general and regional specificity of the structural and functional organization of various glands of organ and system accessories.

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ISSN 2218-7332 (Print)
ISSN 2658-3348 (Online)