A modern view on diagnosis and treatment of the mucocutaneous lymphonodular syndrome (Kawasaki syndrome)
Abstract
The article under review considers the problem of diagnostics and treatment of Kawasaki syndrome in children. The data of modern research, conclusions about the tactics and strategy of treating a disease are given and discussed.
About the Authors
G. A. Lyskina
I.M. Sechenov First MSMU
Russian Federation
Russian Federation
Galina Afanasievna Lyskina, MD, prof. of the chair of childhood diseases
19 B. Pirogovskaya str., Moscow, 119991
8 (499) 248–64–79
O. G. Shirinskaya
I.M. Sechenov First MSMU
Russian Federation
Russian Federation
PhD, senior researcher of the Department of researches in pediatrics of the Research Centre
References
1. Kawasaki T., Kosaki F., Okawa S. et al. A new infantile acute febrile mucocutaneous lymphnode syndrome (MLNS) prevailing in Japan. Pediatrics. 1974; 54: 271–276.
2. Burns J.C. The riddle of Kawasaki disease. N. Engl. J. Med. 2007; 356: 659–661.
3. Lyskina G.A., Shirinskaya O.G. Mucocutaneous limfonodular syndrome (Kawasaki syndrome). Diagnosis and treatment. M.: «Vidar-M». 2008.
4. Rowley A.H., Shulman S.T. Pathogenesis and management of Kawasaki disease. Expert Rev Anti Infect Ther 2010;8:197-203.
5. Lyskina G.A., Vinigradova O.I., Shirinskaya O.G. Kawasaki syndrome in clinical practice: clinical features and treatment of onset of the disease. Ed. by Geppe N.A. M.: «Planida». 2012. 36 p.
6. Lyskina G.A., Shirinskaya O.G. The clinical picture, diagnosis and treatment of the syndrome Kawasaki: known facts and unsolved problems // Voprosy sovremennoj pediatrii. 2013; 1(12): 63-73.
7. Baker A.L., Lu M., Minich L.L. et al. Associated symptoms in the ten days before diagnosis of Kawasaki disease. J. Pediatr. 2009; 154: 592–595
8. Oates-Whitehead RM, Baumer JH, Haines L, et al. Intravenous immunoglobulin for the treatment of Kawasaki disease in children. Cochrane Database Syst Rev 2003:CD004000.
9. Newburger J.W., Takahashi M., Gerber M.A. et al. Diagnosis, treatment, and long-term management of Kawasaki disease: a statement for health professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association. Pediatrics 2004;114:1708-33.
10. Sakata K., Hamaoka K., Ozawa S. et al. A randomized prospective study on the use of 2 g-IVIG or 1 g-IVIG as therapy for Kawasaki disease. Eur. J. Pediatr. 2007; 166: 565–571.
11. Lyskina G.A., Shirinskaya O.G., Vinogradova O.I., Bregel L.V., Subbotin V.M., Burns J. Clinical features, diagnosis and treatment of Kawasaki syndrome. Clinical recommendations. Developed by the Committee of Experts-Russian Public Organization of Association of pediatric cardiologists of Russia, Moscow Department of Health, the staff of the First MSMU named after I.M. Sechenov, Irkutsk SMAPO involving employees of the Scientifi c Center for the Study of Kawasaki disease in United States. M. 2012. 55 p.
12. Hsieh K.S., Weng K.P., Lin C.C., Huang T.C., Lee C.L., Huang S.M. Treatment of acute Kawasaki disease: aspirin’s role in the febrile stage revisited. Pediatrics. 2004; 114(6): 689–693.
13. Burns J.C., Mason W.H. Infl iximab treatment for refractory Kawasaki syndrome. The J. of Pediatr. 2005; 146: 662–667.
14. Jane Burns. Methods for the treatment of acute stage of Kawasaki disease. Doktor Ru. 2013; 9(87): 2-3.
15. Furukawa T., Kishiro M., Akimoto K. et al. Eff ects of steroid pulse therapy on immunoglobulin-resistant Kawasaki disease. Arch. Dis. Child. 2008; 93: 142–146.
16. Orenstein J.M., Shulman S.T., Fox L.M., Baker S.C., Takahashi M., et al. Three linked vasculopathic processes characterize Kawasaki disease: a light and transmission electron microscopic study. PLoS One 7: e3899, 2012.
17. Guidelines for diagnosis and management of cardiovascular sequelae in Kawasaki disease (JCS 2008) — digest version. Circ. J.2010; 74: 1989–2020.
Review
Views:
291
Email this article 